| Chemical & Physical Properties | |
|---|---|
| CAS Number | 935881-37-1 |
| Catalog No. | 2A-0102192 |
| Chinese Name | AR-42 |
| Synonyms | hdac-42; ar 42; osu-hdac42; AR-42 |
| Molecular Formula | C18H20O3N2 |
| Molecular Weight | 312.37 |
| Purity | 96+ |
| Density | 1.223 |
| Appearance | powder |
| Storage Condition | -20℃ |
| EINECS | 0 |
| HTC | 2924299090 |
| UN(IATA) | 0 |
| MDL Number | MFCD17676151 |
| SMILES | CC(C)C(C(=O)Nc1ccc(C(=O)NO)cc1)c1ccccc1 |
| InChI Key | LAMIXXKAWNLXOC-INIZCTEOSA-N |
| MSDS | msds/102192_1_935881_37_1.pdf |
| Use of | Properties Name N-hydroxy-4-[[(2S)-3-methyl-2-phenylbutanoyl]amino]benzamide Synonym More Synonyms AR-42 Biological Activity Related Catalog Research Areas >> Cancer References [1]. Lu YS, Chou CH, Tzen KY, Gao M, Cheng AL, Kulp SK, Cheng JC.Radiosensitizing effect of a phenylbutyrate-derived histone deacetylase inhibitor in hepatocellular carcinoma.Int J Radiat Oncol Biol Phys. 2012 Jun 1;83(2):e181-9. Epub 2012 Feb 28. [2]. Zimmerman B, Sargeant A, Landes K, Fernandez SA, Chen CS, Lairmore MD.Efficacy of novel histone deacetylase inhibitor, AR42, in a mouse model of, human T-lymphotropic virus type 1 adult T cell lymphoma.Leuk Res. 2011 Nov;35(11):1491-7. Epub 2011 Jul 29. [4]. Lin TY et al. AR-42, a novel HDAC inhibitor, exhibits biologic activity against malignant mast cell lines via down-regulation of constitutively activated Kit. Blood. 2010 May 27;115(21):4217-25. Chemical & Physical Properties Molecular Formula C18H20N2O3 Exact Mass 312.14700 PSA 78.43000 LogP 3.64780 InChIKey LAMIXXKAWNLXOC-INIZCTEOSA-N Storage condition -20℃ Safety Information HS Code 2924299090 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 30.0% |
| Transport Info | Product name: Summary 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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