Dicloxacillin sodium structure, CAS 13412-64-1

Dicloxacillin sodium

CAS Number13412-64-1

SynonymsDicloxacillin sodium salt monohydrate; Dicloxacillin sodium; MFCD00210902; EINECS 206-444-3; Dicloxacillin (Sodium hydrate)

Molecular FormulaC19H18Cl2N3NaO6S

Molecular Weight510.32

Purity98%

Density

Boiling Point692.4ºC at 760mmHg

Melting Point222-225°C

Flash Point

AppearanceWhite to off-white crystalline powder

EINECS

MSDSChineseEnglish

Symbol

Signal Word

Cat. No.: 2A-9010128 Purity: 98%
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Quality Control of [ 13412-64-1 ] Purity: 98% SDS Specification MoL

Chemical & Physical Properties
CAS Number13412-64-1
Catalog No.2A-9010128
Chinese Name双氯西林钠
SynonymsDicloxacillin sodium salt monohydrate; Dicloxacillin sodium; MFCD00210902; EINECS 206-444-3; Dicloxacillin (Sodium hydrate)
Molecular FormulaC19H18Cl2N3NaO6S
Molecular Weight510.32
Purity98
Boiling Point692.4ºC at 760mmHg
Melting Point222-225°C
AppearanceWhite to off-white crystalline powder
Storage Condition2-8°C
ApplicationDicloxacillin NaOH is a narrow-spectrum β-lactam antibiotic of the penicillin family, which can treat Gram-positive bacterial infections and is effective against β-lactamase-producing microorganisms s
HTC2941109900
PubChem ID329749567
MDL NumberMFCD00167147
SMILESO.[Na+].Cc1onc(c1C(=O)N[C@H]2[C@H]3SC(C)(C)[C@@H](N3C2=O)C([O-])=O)-c4c(Cl)cccc4Cl
InChI1S/C19H17Cl2N3O5S.Na.H2O/c1-7-10(12(23-29-7)11-8(20)5-4-6-9(11)21)15(25)22-13-16(26)24-14(18(27)28)19(2,3)30-17(13)24;;/h4-6,13-14,17H,1-3H3,(H,22,25)(H,27,28);;1H2/q;+1;/p-1/t13-,14+,17-;;/m1../s1
InChI KeySIGZQNJITOWQEF-VICXVTCVSA-M
NACRES CodeNA.24
UNSPSC41116107
MSDSmsds/10128_1_13412_64_1.pdf
Use ofDicloxacillin NaOH is a narrow-spectrum β-Lactam antibiotic of the penicillin class, is used to treat infections caused by susceptible Gram-positive bacteria, active against beta-lactamase-producing organisms such as Staphylococcus aureus. Properties Articles30 Name dicloxacillin sodium monohydrate Synonym More Synonyms Dicloxacillin sodium Biological Activity Description Dicloxacillin NaOH is a narrow-spectrum β-Lactam antibiotic of the penicillin class, is used to treat infections caused by susceptible Gram-positive bacteria, active against beta-lactamase-producing organisms such as Staphylococcus aureus. Related Catalog Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection Chemical & Physical Properties Exact Mass 509.019104 PSA 150.10000 LogP 2.13190 InChIKey QBFCIKYALGTFHK-VICXVTCVSA-N Toxicological Information CHEMICAL IDENTIFICATION RTECS NUMBER : CHEMICAL NAME : 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(3-(2,6-dichlorophenyl)-5-methyl- 4-isoxazolecarboxamido)-3,3-dimethyl-7-oxo-, monosodium salt, monohydrate CAS REGISTRY NUMBER : 13412-64-1 LAST UPDATED : DATA ITEMS CITED : MOLECULAR FORMULA : C19-H16-Cl2-N3-O5-S.Na.H2-O MOLECULAR WEIGHT : WISWESSER LINE NOTATION : T45 ANV ESTJ F1 F1 GVQ CMV- DT5NOJ C1 ER BG FG &-NA- HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : SPECIES OBSERVED : Human - man DOSE/DURATION : TOXIC EFFECTS : Behavioral - anorexia (human) Gastrointestinal - other changes Liver - jaundice, cholestatic REFERENCE : JCGADC Journal of Clinical Gastroenterology. (Raven Press, 1185 Ave. of the Americas, New York, NY 10036) Volume(issue)/page/year: 8,77,1986 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : SPECIES OBSERVED : Rodent - rat DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 18,185,1971 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 15,322,1965 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : TOXIC EFFECTS : Lungs, Thorax, or Respiration - dyspnea Gastrointestinal - other changes Liver - other changes REFERENCE : JJANAX Japanese Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo 141, Japan) V.21- 1968- Volume(issue)/page/year: 21,274,1968 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : TOXIC EFFECTS : Lungs, Thorax, or Respiration - dyspnea Gastrointestinal - other changes Liver - other changes REFERENCE : JJANAX Japanese Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo 141, Japan) V.21- 1968- Volume(issue)/page/year: 21,274,1968 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : TOXIC EFFECTS : Lungs, Thorax, or Respiration - dyspnea Gastrointestinal - other changes Liver - other changes REFERENCE : JJANAX Japanese Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo 141, Japan) V.21- 1968- Volume(issue)/page/year: 21,274,1968 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : TOXIC EFFECTS : Lungs, Thorax, or Respiration - dyspnea Gastrointestinal - other changes Liver - other changes REFERENCE : JJANAX Japanese Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo 141, Japan) V.21- 1968- Volume(issue)/page/year: 21,274,1968 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : TOXIC EFFECTS : Lungs, Thorax, or Respiration - dyspnea Gastrointestinal - other changes Liver - other changes REFERENCE : JJANAX Japanese Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo 141, Japan) V.21- 1968- Volume(issue)/page/year: 21,274,1968 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : SPECIES OBSERVED : Mammal - dog DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JJANAX Japanese Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo 141, Japan) V.21- 1968- Volume(issue)/page/year: 21,274,1968 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JJANAX Japanese Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo 141, Japan) V.21- 1968- Volume(issue)/page/year: 21,274,1968 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : TOXIC EFFECTS : Lungs, Thorax, or Respiration - dyspnea Gastrointestinal - other changes Liver - other changes REFERENCE : JJANAX Japanese Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo 141, Japan) V.21- 1968- Volume(issue)/page/year: 21,274,1968 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4575 No. of Facilities: 73 (estimated) No. of Industries: 2 No. of Occupations: 7 No. of Employees: 1518 (estimated) No. of Female Employees: 606 (estimated) Safety Information GHS07, GHS08 Signal Word Danger Hazard Statements H315-H319-H334-H335 Precautionary Statements P261-P284-P304 + P340-P305 + P351 + P338-P342 + P311 Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves Hazard Codes Xn: Harmful; RIDADR NONH for all modes of transport WGK Germany 2 RTECS XH8925000 HS Code 2941109900
Transport InfoProduct Name: Dicloxacillin Sodium
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