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(S)-2-(5,5-DIMETHYLMORPHOLIN-2-YL)ACETIC ACID

Name: (S)-2-(5,5-DIMETHYLMORPHOLIN-2-YL)ACETIC ACID
Brand: 2A Biotech
SKU: 2A-0101107

CAS Number160415-07-6

Synonyms(+)-(2S)-5,5-Dimethyl-2-morpholineacetic acid hydrochloride

Molecular FormulaC12H12O2N1Cl1

Molecular Weight237.69

Purity96+%

Density1.055 g/cm3

Boiling Point305.5ºC at 760 mmHg

EINECS0

MSDSChinese English

Symbol

Signal WordWarning

Cat. No.: 2A-0101107 Purity: 96+%

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Quality Control of [ 160415-07-6 ] Purity: 96+% SDS Specification MoL

Chemical & Physical Properties
CAS Number	160415-07-6
Catalog No.	2A-0101107
Chinese Name	(S)-2-(5,5-二甲基吗啉-2-基)乙酸盐酸盐
Synonyms	(+)-(2S)-5,5-Dimethyl-2-morpholineacetic acid hydrochloride
Molecular Formula	C12H12O2N1Cl1
Molecular Weight	237.69
Purity	96+
Density	1.055 g/cm3
Boiling Point	305.5ºC at 760 mmHg
Storage Condition	room temperature
Application	SCH 50911 hydrochloride, an orally active, selective and competitive gamma-aminobutyric acid B GABA(B) receptor antagonist, binds to the GABA(B) receptor with an IC50 of 1.1 μM. SCH 50911 hydrochlorid
EINECS	0
HTC	2934999090
UN(IATA)	0
MDL Number	MFCD31706472
SMILES	CC1(C)COC(CC(=O)O)CN1.Cl
InChI Key	QYYBBASPKHNBKA-RGMNGODLSA-N
Hazard Symbols	transportation
MSDS	msds/101107_1_160415_07_6.pdf
Bioactivity	SCH 50911 hydrochloride, (+)-(S)-5,5-dimethylmorpholinyl-2-acetic acid, a selective, orally-active and competitive γ-Aminobutyric acid B GABA(B) receptor antagonist, binds to GABA(B) receptor with IC50 of 1.1 μM. SCH 50911 hydrochloride antagonizes GABA(B) autoreceptors, increasing the electrically-stimulated 3H overflow with an IC50 of 3 μM. Related Catalog Signaling Pathways >> Membrane Transporter/Ion Channel >> GABA Receptor Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> GABA Receptor Target GABA(B):1.1 μM (IC50) References [1]. Ong J, et al. The morpholino-acetic acid analogue Sch 50911 is a selective GABA(B) receptor antagonist in rat neocortical slices. Eur J Pharmacol. 1998 Nov 27;362(1):35-41. Chemical & Physical Properties Density 1.055 g/cm3 Boiling Point 305.5ºC at 760 mmHg Molecular Formula C8H16ClNO3 Molecular Weight 173.21000 Flash Point 138.6ºC Exact Mass 173.10500 PSA 58.56000 LogP 0.55690 Vapour Pressure 0.000187mmHg at 25°C Index of Refraction 1.444 InChIKey QYYBBASPKHNBKA-RGMNGODLSA-N SMILES CC1(C)COC(CC(=O)O)CN1.Cl
Use of	SCH 50911 hydrochloride, (+)-(S)-5,5-dimethylmorpholinyl-2-acetic acid, a selective, orally-active and competitive γ-Aminobutyric acid B GABA(B) receptor antagonist, binds to GABA(B) receptor with IC50 of 1.1 μM. SCH 50911 hydrochloride antagonizes GABA(B) autoreceptors, increasing the electrically-stimulated 3H overflow with an IC50 of 3 μM. Properties Name (2s)-(+)-5,5-dimethyl-2-morpholineacetic acid Synonym More Synonyms SCH 50911 hydrochloride Biological Activity Description SCH 50911 hydrochloride, (+)-(S)-5,5-dimethylmorpholinyl-2-acetic acid, a selective, orally-active and competitive γ-Aminobutyric acid B GABA(B) receptor antagonist, binds to GABA(B) receptor with IC50 of 1.1 μM. SCH 50911 hydrochloride antagonizes GABA(B) autoreceptors, increasing the electrically-stimulated 3H overflow with an IC50 of 3 μM. Related Catalog Signaling Pathways >> Membrane Transporter/Ion Channel >> GABA Receptor Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> GABA Receptor GABA(B):1.1 μM (IC50) References [1]. Ong J, et al. The morpholino-acetic acid analogue Sch 50911 is a selective GABA(B) receptor antagonist in rat neocortical slices. Eur J Pharmacol. 1998 Nov 27;362(1):35-41. Chemical & Physical Properties Exact Mass 173.10500 PSA 58.56000 LogP 0.55690 Index of Refraction 1.444 InChIKey QYYBBASPKHNBKA-RGMNGODLSA-N
Tax Rebate	13.0%
Supervision	None. MFN tariff: 6.5%. Ordinary tariff: 20.0%
Transport Info	Shipping Name: UN
MSDS Transport Info	Module 14. Shipping information 14.1 United Nations number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special precautions No data available

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(S)-2-(5,5-DIMETHYLMORPHOLIN-2-YL)ACETIC ACID

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